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DESCRIPTION:Oscillator theory meets biological rhythms\n\nHanspeter Herzel\
 , Institute for Theoretical Biology (ITB)\n	Tuesday March 19\, 12-1pm\n	Zoom
  Link: https://mcgill.zoom.us/j/86855481591\n	In Person: 550 Sherbrooke\, R
 oom 189\n	\n	Abstract: Oscillations in biological systems appear on many tim
 e scales from millisecond vibrations of vocal folds\, via heart rhythms\, 
 to circadian rhythms with a period of 24 hours. Oscillator theory (limit c
 ycles\, Hopf bifurcation\, Arnold's tongues) provides a framework to under
 stand the emergence and interaction of biomedical rhythms. In the first pa
 rt\, I review oscillator theory using examples from voice production\, phy
 siological rhythms\, and transcriptional feedback loops. I introduce conce
 ptual mathematical models (Poincare oscillator\, Goodwin model) illustrati
 ng the role of nonlinearities\, feedbacks\, and resonances. In the second 
 part\, I describe circadian clocks as a coupled oscillator system. Even si
 ngle cells exhibit rhythms due to genetic feedback loops. The coupling of 
 SCN neurons allows the adaptation to light-dark cycles and the orchestrati
 on of body clocks. Oscillator theory helps to understand the features of c
 hronotypes and jetlag. Finally\, simulations can contribute to the optimiz
 ation of chronotherapy.\n
DTSTART:20240319T160000Z
DTEND:20240319T170000Z
SUMMARY:QLS Seminar Series - Hanspeter Herzel
URL:/qls/channels/event/qls-seminar-series-hanspeter-h
 erzel-355349
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