BEGIN:VCALENDAR VERSION:2.0 PRODID:-//132.216.98.100//NONSGML kigkonsult.se iCalcreator 2.20.4// BEGIN:VEVENT UID:20250806T085701EDT-81101f18Wv@132.216.98.100 DTSTAMP:20250806T125701Z DESCRIPTION:'Born that way: The role of initial state in the formation\, st ability and function of the mitotic spindle'\n\nJackie Vogel\, 91ºÚÁÏÍø Univ eristy\n Tuesday October 2\, 12-1pm\n McIntyre Building\, Room 1027\n \n Abstr act: The process of forming a bipolar spindle requires the coordination of force generating and microtubule crosslinking proteins with the dynamical properties of microtubules to first separate duplicated spindle poles and subsequently to execute chromosome attachment and bio-orientation. The pr ocess of spindle assembly has been studied extensively in the unicellular fungus budding yeast\, a unicellular eukaryote. This organism has a spindl e architecture that is economical and yet shares design features of more c omplex spindles in animal cells. In this talk\, I will describe our biophy sical analysis of how the initial state of a monopolar spindle contributes to the fast\, switch-like and irreversible formation of a bipolar spindle as well as the stability of new spindles.\n DTSTART:20181002T160000Z DTEND:20181002T170000Z LOCATION:Room 1027\, McIntyre Medical Building\, CA\, QC\, Montreal\, H3G 1 Y6\, 3655 promenade Sir William Osler SUMMARY:Seminar Series in Quantitative Life Sciences and Medicine URL:/qls/channels/event/seminar-series-quantitative-li fe-sciences-and-medicine-289931 END:VEVENT END:VCALENDAR