BEGIN:VCALENDAR VERSION:2.0 PRODID:-//132.216.98.100//NONSGML kigkonsult.se iCalcreator 2.20.4// BEGIN:VEVENT UID:20250816T125158EDT-9048t0vXbK@132.216.98.100 DTSTAMP:20250816T165158Z DESCRIPTION:\n Neurons communicate with one another through highly-plastic m icroscopic structures called synapses. The receiving end of these communic ation structures\, called dendritic spines\, undergo massive nano-structur al and functional alterations in various health and disease contexts. Thes e dendritic spine changes rely on precise cytoskeletal rearrangements\, as well as communication with surrounding glial cells. The pannexin 1 ATP-re lease channel is well-positioned as a dendritic spine regulator via its (1 ) interactions with spine cytoskeleton regulators\, and (2) capacity for p urinergic receptor-mediated communication with glial cells. Given pannexin 1 expression levels\, function\, and trafficking are dramatically altered during postnatal development and inflammation/injury\, this complex dual role for pannexin 1 has several neurological disease implications.\n\nThis seminar will be offered both in-person and online. Details in attached po ster.\n DTSTART:20211203T160000Z DTEND:20211203T170000Z LOCATION:Room 1034\, McIntyre Medical Building\, CA\, QC\, Montreal\, H3G 1 Y6\, 3655 promenade Sir William Osler SUMMARY:Seminar - Dynamic neuronal connections in health and disease: dual role for pannexin 1 URL:/physiology/channels/event/seminar-dynamic-neurona l-connections-health-and-disease-dual-role-pannexin-1-334086 END:VEVENT END:VCALENDAR