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UID:20250820T170550EDT-4044mr0ckE@132.216.98.100
DTSTAMP:20250820T210550Z
DESCRIPTION:\n	Hematopoietic stem cells (HSC)\, or blood forming stem cells\
 , are found in the adult bone marrow\, where they are essential for the co
 ntinuous generation of circulating blood cells\, including the cells of th
 e immune system. Their function is normally tightly regulated\, and the di
 fferent types of blood cells are being produced in balanced quantities. In
  a situation of stress\, such as an acute infection\, HSCs become activate
 d\, and the proportions of the different blood cells being produced will c
 hange in a process called emergency hematopoiesis. The major goal of this 
 adaptation is to better respond to the infection and to eliminate the infe
 ctious agent. However\, our recent work suggests that persistent pathogens
  may actually use the HSCs to escape the immune response by modifying the 
 emergency response in favor of specific types of blood cells. We believe t
 hese mechanisms are actually crucial for the establishment of persistent i
 nfections\, and now aim at better understanding how this happens and how i
 t could be used to develop efficient therapies.\n\nThis seminar is availab
 le both in-person and via Zoom. Details in attached poster.\n\n**Masks and
  1 m distancing required**\n
DTSTART:20211029T150000Z
DTEND:20211029T160000Z
LOCATION:Room 1034\, McIntyre Medical Building\, CA\, QC\, Montreal\, H3G 1
 Y6\, 3655 promenade Sir William Osler
SUMMARY:In-person seminar - Bone marrow emergency response to infections: G
 ood or bad but most often ugly
URL:/physiology/channels/event/person-seminar-bone-mar
 row-emergency-response-infections-good-or-bad-most-often-ugly-333606
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