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UID:20250818T063607EDT-3254pkwnJT@132.216.98.100
DTSTAMP:20250818T103607Z
DESCRIPTION:Neural circuits display complex spatiotemporal patterns of acti
 vity on the millisecond timescale during behavior. Understanding how these
  activity patterns drive behavior is a fundamental problem in neuroscience
 \, and remains a major challenge due to the complexity of their spatiotemp
 oral dynamics. The ability to manipulate activity in genetically defined s
 ets of neurons on the millisecond timescale using optogenetics has provide
 d a powerful new tool for making causal links between neuronal activity an
 d behavior. I will discuss novel approaches that combine simultaneous two-
 photon calcium imaging and two-photon targeted optogenetic photostimulatio
 n with the use of a spatial light modulator (SLM) to provide ‘all-optical’
  readout and manipulation of the same neurons in vivo. This approach enabl
 es reading and writing of activity in neural circuits with single-cell res
 olution and single action potential precision during behavior. I will desc
 ribe the power\, limitations and future potential of this approach\; and d
 iscuss how it can be used to address many important problems in neuroscien
 ce\, including transforming our search for the neural code and the links b
 etween neural circuit activity and behavior.\n\nThis event is sponsored by
  CAMBAM.\n\n \n
DTSTART:20191206T160000Z
DTEND:20191206T170000Z
LOCATION:Room 1034\, McIntyre Medical Building\, CA\, QC\, Montreal\, H3G 1
 Y6\, 3655 promenade Sir William Osler
SUMMARY:Seminar - Technologies for all-optical interrogation of neural circ
 uits in behaving animals
URL:/physiology/channels/event/seminar-technologies-al
 l-optical-interrogation-neural-circuits-behaving-animals-300739
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