BEGIN:VCALENDAR VERSION:2.0 PRODID:-//132.216.98.100//NONSGML kigkonsult.se iCalcreator 2.20.4// BEGIN:VEVENT UID:20251121T124726EST-8496Z6VLDa@132.216.98.100 DTSTAMP:20251121T174726Z DESCRIPTION:Supported by the generosity of the Killam Trusts\, the MNI's Ki llam Seminar Series invites outstanding guest speakers whose research is o f interest to the scientific community at the MNI and 91ºÚÁÏÍø.\n \n\nTo attend in person\, click (here)\n\nTo watch virtually\, click (here )\n\nJeremy Dittman\, PhD\n\nAssociate Professor of Biochemistry and Neuro science\, Weill Cornell Medicine\, New York\, USA\n\nHost: Wayne Sossin\n \nAbstract: The mechanisms underlying synaptic vesicle docking\, priming\, and fusion have remained long-standing mysteries in molecular neuroscienc e. Munc13 (an essential presynaptic protein) governs vesicle capture\, SNA RE assembly\, and fusion while complexin maintains vesicles in a ready sta te by inhibiting spontaneous fusion. New structural and biochemical findin gs and analysis of human mutations have helped shape a more complete pictu re of the events preceding vesicle fusion and the regulation of synaptic t ransmission.\n DTSTART:20231114T210000Z DTEND:20231114T220000Z SUMMARY:Killam Seminar Series: Molecular Basis of Synaptic Vesicle Fusion: New Insights into Munc13 and Complexin Function URL:/neuro/channels/event/killam-seminar-series-molecu lar-basis-synaptic-vesicle-fusion-new-insights-munc13-and-complexin-352393 END:VEVENT END:VCALENDAR