91ºÚÁÏÍø

Supported by the generosity of the Killam Trusts, The Neuro's Killam Seminar Series invites outstanding guest speakers whose research is of interest to the scientific community at The Neuro and 91ºÚÁÏÍø.

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The role of BDNF in hormonal regulation of seizures in temporal lobe epilepsy

Abstract: One of the long-standing questions in epilepsy research is why seizures are so sensitive to the influence of gonadal hormones. In this seminar, data will be presented to support the novel hypothesis that steroid receptors acting on their target genes provide an explanation, and focus on the gene for brain-derived neurotrophic factor, a neurotrophin known for its influence on neurodevelopment and the mature brain. The results shed light not only on epilepsy but also many aspects of normal function and diverse neurological and psychiatric disorders.

Helen E. Scharfman

New York University Grossman School of Medicine and The Nathan Kline Institute for Psychiatric Research

Dr. Scharfman has contributed broadly in basic and translational neuroscience. She has served on numerous advisory boards for national and international organizations, such as the American Epilepsy Society, the Epilepsy Foundation, Citizens United for Research on Epilepsy, and Parents Against Childhood Epilepsy.