BEGIN:VCALENDAR VERSION:2.0 PRODID:-//132.216.98.100//NONSGML kigkonsult.se iCalcreator 2.20.4// BEGIN:VEVENT UID:20250913T103242EDT-8899Jel3L8@132.216.98.100 DTSTAMP:20250913T143242Z DESCRIPTION:Mélanie Henderson\, PhD\n\nClinical Assistant Professor\, Unive rsité de Montréal & Researcher\, Research Center of CHU Sainte-Justine\n\n Lifestyle habits and the risk of Diabetes in youth: what’s the evidence? … and what can we do with it?\n\nALL ARE WELCOME\n\nSYNOPSIS:\n\nDecreased insulin sensitivity and impaired pancreatic B-cell function have been iden tified as key components in the pathogenesis of type 2 diabetes mellitus. Given the obesity epidemic in Canadian children\, pre-diabetes and early t ype 2 diabetes are emerging concerns. In adults\, extensive evidence shows that lifestyle modifications prevent or delay the transition from pre-dia betes states such as impaired fasting glucose and impaired glucose toleran ce to type 2 diabetes mellitus with up to 58% decreased progression. Howev er\, the impact of physical activity\, fitness and sedentary behavior on g lucose homeostasis remains poorly understood in children and adolescents. Recent data from American children estimate that the prevalence of pre-dia betes has increased by 87% over a 5-year-period\, and Canadian figures put obese youth at highest risk for pre-diabetes. Moreover\, only 4-7% of Can adian children and youth are currently meeting physical activity guideline s. In addition 31% of Canadian children and 69% of youth exceed the recomm ended maximum of 2 hours of ST daily. Understanding the link between adipo sity\, physical activity\, sedentary behavior\, fitness and abnormal gluco se metabolism is essential to the development of effective preventive stra tegies.\n\nOBJECTIVES:\n\n1) To understand the role of physical activity a nd sedentary behavior in the pathogenesis of type 2 diabetes and pre-diabe tes in childhood\;\n\n2) To understand the role of dietary habits in the p athogenesis of type 2 diabetes and pre-diabetes in childhood\;\n\n3) To ga in insight into the clinical applicability of this type of research.\n\nBI O:\n\nMélanie Henderson completed her training in occupational therapy pri or to pursuing her studies in medicine at 91ºÚÁÏÍø. She did her s pecialty training in pediatrics and 2 years of subspecialty training in pe diatric endocrinology at the Hospital for Sick Children (University of Tor onto). She completed a third year of pediatric endocrinology training at C HU Sainte-Justine (Université de Montréal). During her subspecialty traini ng\, she completed her Master’s in epidemiology at University of Toronto\, and went on to complete her PhD in epidemiology at 91ºÚÁÏÍø. She is a clinical assistant professor at Université de Montréal\, and a resea rcher at the Research Center of CHU Sainte-Justine. Her research interests focus on obesity\, diabetes and cardiovascular disease risk factors in ch ildhood.\n\n \n\nwww.mcgill.ca/epi-biostat-occh/news-events/seminars/epide miology\n DTSTART:20160125T210000Z DTEND:20160125T220000Z LOCATION:Room 521\, McIntyre Medical Building\, CA\, QC\, Montreal\, H3G 1Y 6\, 3655 promenade Sir William Osler SUMMARY:Epidemiology Seminar URL:/epi-biostat-occh/channels/event/epidemiology-semi nar-257783 END:VEVENT END:VCALENDAR