BEGIN:VCALENDAR VERSION:2.0 PRODID:-//132.216.98.100//NONSGML kigkonsult.se iCalcreator 2.20.4// BEGIN:VEVENT UID:20250913T093515EDT-68920AXGKX@132.216.98.100 DTSTAMP:20250913T133515Z DESCRIPTION:Sherri Rose\, PhD\n\nAssistant Professor\, Department of Health Care Policy\, Harvard Medical School\n\nA Robust Machine-Learning Approac h for Variable Importance in Health Spending\n\nALL ARE WELCOME\n\nAbstrac t:\n\nThe impact of medical conditions on health care spending has almost exclusively been examined in parametric regression for health plan payment risk adjustment. This paper presents nonparametric machine-learning-based effect estimators for variable importance to understand the role of indiv idual medical condition categories in health spending among commercially i nsured enrollees. We evaluate how much more\, on average\, enrollees with each medical condition cost after controlling for demographic information and other medical conditions. This is accomplished within the targeted lea rning framework using targeted maximum likelihood estimation and super lea rning to estimate the effects of these medical conditions. Our results dem onstrate that multiple sclerosis\, congestive heart failure\, severe cance rs\, major depression and bipolar disorders\, and chronic hepatitis are th e most costly medical conditions on average per individual.  In contrast\, standard parametric regression formulas for plan payment risk adjustment differed nontrivially both in the size of effect estimates and relative ra nks. The health spending literature may be considerably underestimating th e spending contributions of a number of medical conditions\, which is a po tentially critical oversight. If current risk-adjustment methods are not c apturing the true incremental effect of medical conditions\, undesirable i ncentives related to adverse selection in health insurance markets may rem ain.\n\nBio:\n\nwww.drsherrirose.com\n\n \n\n \n DTSTART:20160405T193000Z DTEND:20160405T203000Z LOCATION:Room 24\, Purvis Hall\, CA\, QC\, Montreal\, H3A 1A2\, 1020 avenue des Pins Ouest SUMMARY:Biostatistics Seminar: 'A Robust Machine-Learning Approach for Vari able Importance in Health Spending' URL:/epi-biostat-occh/channels/event/biostatistics-sem inar-robust-machine-learning-approach-variable-importance-health-spending- 259541 END:VEVENT END:VCALENDAR