BEGIN:VCALENDAR VERSION:2.0 PRODID:-//132.216.98.100//NONSGML kigkonsult.se iCalcreator 2.20.4// BEGIN:VEVENT UID:20260525T145718EDT-6380VTAxXU@132.216.98.100 DTSTAMP:20260525T185718Z DESCRIPTION:Abstract\n\nAlthough Deep Learning (DL) models have been shown to perform very well on various medical imaging tasks\, inference in the p resence of pathology presents several challenges to common models. These c hallenges impede the integration of DL models into real clinical workflows . Deployment of these models into real clinical contexts requires: (1) tha t the confidence in DL model predictions be accurately expressed in the fo rm of uncertainties and (2) that they exhibit robustness and fairness acro ss different sub-populations. Quantifying the reliability of DL model pred ictions in the form of uncertainties could enable clinical review of the m ost uncertain regions\, thereby building trust and paving the way toward c linical translation. Similarly\, by embedding uncertainty estimates across cascaded inference tasks\, prevalent in medical image analysis\, performa nce on the downstream inference tasks should also be improved. In this the sis\, we develop an uncertainty quantification score for the task of Brain Tumour Segmentation. We evaluate the score's usefulness during the two ch allenges\, BraTS 2019 and BraTS 2020. Overall\, our findings confirm the i mportance and complementary value that uncertainty estimates provide to se gmentation algorithms\, highlighting the need for uncertainty quantificati on in medical image analyses. We further show the importance of uncertaint y estimates in medical image analysis by propagating uncertainty generated by upstream tasks into the downstream task of interest. Our results on th ree different clinically relevant tasks indicate that uncertainty propagat ion helps improve the performance of the downstream task of interest. Addi tionally\, we combine the aspect of uncertainty estimates with fairness ac ross demographic subgroups into the picture. With extensive experiments on multiple tasks\, we show that popular ML methods for achieving fairness a cross different subgroups\, such as data-balancing and distributionally ro bust optimization\, succeed in terms of the model performances for some of the tasks. However\, this can come at the cost of poor uncertainty estima tes associated with the model predictions. This tradeoff must be mitigated if fairness models are to be adopted in medical image analysis. In the la st part of the thesis\, we look at Active Learning (AL) for reduced manual labeling of a dataset. Specifically\, we present an information-theoretic AL framework that guides the optimal selection of images for labeling. Re sults indicate that the proposed framework outperforms several existing me thods\, and by careful design choices\, it can be integrated into existing DL classifiers with minimal computational overhead.\n DTSTART:20230705T180000Z DTEND:20230705T200000Z LOCATION:Room 603\, McConnell Engineering Building\, CA\, QC\, Montreal\, H 3A 0E9\, 3480 rue University SUMMARY:PhD defence of Raghav Mehta – Integrating Bayesian Deep Learning Un certainties in Medical Image Analysis URL:/ece/channels/event/phd-defence-raghav-mehta-integ rating-bayesian-deep-learning-uncertainties-medical-image-analysis-348930 END:VEVENT END:VCALENDAR