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UID:20260710T191216EDT-7730zDlseZ@132.216.98.100
DTSTAMP:20260710T231216Z
DESCRIPTION:Department of Human Genetics Guest\nLecture:\n\nWednesday\, Apr
 il 6\, 2011 ~ 3:30pm\nStewart Biology Building Room W4/12\n\nTitle: 'Neura
 l stem cells: from development to\nrepair”\n\nFreda Miller\, Ph.D.\nProfes
 sor\nUniversity of Toronto\nHospital for Sick Children\n \nAbstract:\nThis
  lecture will focus upon the field of mammalian neural stem\ncells and pre
 cursors from two perspectives. The first part of the\nlecture will focus o
 n the mechanisms regulating self-renewal versus\ndifferentiation of embryo
 nic neural precursors\, and how this is\nperturbed in genetic syndromes th
 at cause cognitive dysfunction.\nThe second part will focus upon multipote
 nt\, neural crest-like\ndermal precursors (Skin-derived Precursors or SKPs
 ) both with\nregard to their basic biology and their potential therapeutic
  use\nfor treatment of the damaged nervous system.\nAbout the Speaker:\nDr
 . Freda Miller is a cell and molecular developmental\nneurobiologist at th
 e Hospital for Sick Children Research\nInstitute\, Professor at University
  of Toronto. She is the Canada\nResearch Chair in Developmental Neurobiolo
 gy\, a Howard Hughes\nMedical Institute International Research Scholar\, a
  Fellow of the\nRoyal Society of Canada\, and the Secretary of the America
 n Society\nfor Neurosciences. Dr. Miller has authored more than 120 scient
 ific\npapers\, reviews and book chapters and has 15 patents (issued and\np
 ending).\n\nDr. Miller is best known for her studies of neural stem cells 
 and\nof neuronal growth\, survival and apoptosis. Major findings from her
 \nlab have provided evidence that adult mammalian skin contains an\naccess
 ible multipotent dermal stem cell that can generate\nperipheral neural cel
 ls\, that the p75 neurotrophin receptor\nmediates apoptosis and axonal deg
 eneration\, that the p53 family\nmembers\, p73 and p63 play a critical rol
 e in determining the life\,\ndeath and degeneration of mammalian neurons\,
  and that one way\ngenetic disorders cause cognitive dysfunction is by per
 turbing\nembryonic neurogenesis.\nDr. Miller obtained her PhD in Medical S
 ciences from the University\nof Calgary and completed her postdoctoral tra
 ining at the Scripps\nResearch Foundation. She then held faculty positions
  at the\nUniversity of Alberta and the Montreal Neurological Institute at
 \n91������ prior to moving to her current position in 2002.\nDr. 
 Miller is also a founder of Aegera Therapeutics Inc.\, a\nCanadian biotech
 nology company.\n \n \n
DTSTART:20110406T193000Z
DTEND:20110406T193000Z
LOCATION:Stewart Biology Building\, CA\, QC\, Montreal\, H3A 1B1\, 1205 ave
 nue du Docteur-Penfield
SUMMARY:'Neural stem cells: from development to repair'
URL:/channels/event/neural-stem-cells-development-repa
 ir-173350
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